[Hypothesis] Remote neural monitoring based on magnetic resonance in the Earth's magnetic field and biocorrelation

Remote functional MRI beyond fMRI-BOLD using the proton and electron resonance signal on the basis of MR current density imaging (MRCDI)

The equivalent of a nuclear and electron spin magnetic resonance magnetoencephalogram (NMR MEG and ESR MEG)

 

 

Brain and body electromagnetism represent an electric/magnetic flux of small intensity which is difficult to measure remotely. However, upon a certain excitation event and specifically spin excitation in the frame of magnetic resonance, it is possible to generate a measurable electric/magnetic flux.

 

How do we compensate for the low static magnetic field strength of the Earth's magnetic field?

I. Surface NMR

Well NMR logging

Surface NMR in large scale is conducted in Earth's magnetic field for groundwater and oil detection

 

Well NMR logging in conducted in Earth's magnetic field or low magnetic fields (rock magnetization using probe)

II. Advances in low-field MRI and Earth's field MRI

Commercial scanners for brain low-field MRI and generic Earth's field NMR/MRI exist

 

Significant advances in ultra low-field MRI: 6.5 mT (vs 1.5 T of typical scanner) by using specific pulse sequences 

 

IIa. Pulse sequence design

 

e.g. balanced Steady-State-Free-Precession (b-SSFP) sequences

 

Dynamic refocusing of spins after measurement 

 

Can only work in homogeneous fields (advantage of low fields)

IIb. Undersampling (sparse sampling)  

Only the best, most representative features are sampled

 

(Noise discarded by default)

 

 

 

 

IIc. Magnetic Resonance fingerprinting

MR fingerprints are matched using pattern recognition algorithms to predefined dictionary of predicted signal evolutions

 

Multiparametric analyses similar to genomic or proteomic analyses

III. Circularly polarized electromagnetic radiation

Improvement of signal-to-noise ratio, decrease of artifacts, reduction of excitation power 

IV. Circularly polarized light in remote optical magnetometry (LGS)

Optical polarization: Excitation of a specific electron transition with circularly polarized light generates an electron reconfiguration which creates a charged atom pole thereby mediating atom polarization. 

V. Hyperpolarization

Techniques to mediate polarization transfer between nuclear spins and from electron spins to nuclear spins.

Dynamic Nuclear Polarization (DNP), Spin exchange optical pumping etc.

VI. Combination of MRI with ESR

Polarization transfer from electrons

 

Overhauser Magnetic Resonance Imaging (OMRI) or Proton Electron Double Resonance Imaging (PEDRI)

VIIa. Quasi-static electric and magnetic fields 

 

 

In the near field region of less than one wavelength, electric and magnetic fields are quasi-static

 

 

VIIb. EM waves below 14 MHz are quasi-static for the human body

 

RNM hypothesis:

A static magnetic field can be created at a specific location using an ELF wave etc. to enhance phenomena

VIII. Static and low frequency fields generate charges on body surface or environment

RNM hypothesis: Possibility to use proton and electron double resonance (cf. electron clouds) & Aharonov-Bohm detection

IX. Ionization by microwaves - charge generation on body surface or environment

RNM hypothesis:

(same as VIII)

RNM device reading electron changes

Gyrotron pulsed-power device surrounding subject in microwave and reading electron changes